Monitoring levels of human cytomegalovirus DNA in blood after liver transplantation.
E Drouet, R Colimon, S Michelson...
https://pubmed.ncbi.nlm.nih.gov/7714198Completed
All Genders
ID00001477
Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to Therapy
Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2008-03-04
300
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients are exposed to infectious agents regularly, regardless of their immunologic status. Traditionally clinicians have decided to institute prophylaxis based on epidemiologic factors, skin test (i.e. PPD), or immunologic parameters. A quantitative and specific method that is non-invasive, such as quantitative PCR, would be desirable to more precisely define those who would benefit from prophylaxis. Similarly, when patients develop disease and are being treated, quantitative, non-invasive techniques are needed to assess response to therapy. This project is designed to develop and test quantitative tests using blood, urine, or sputum samples.
CONDITIONS
Official Title
Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to Therapy
Who Can Participate
All Genders
Eligibility Criteria
You may qualify if you...
Patients older than 18 years of age.
Ability to give informed consent.
No medical contraindication to phlebotomy.
Epidemiologically at risk for tuberculosis or for an opportunistic infection.
Patients who can identify a responsible health care provider as someone willing to provide clinical information and to receive medically important information.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Detection of cytomegalovirus DNA in sera of liver transplant recipients.
R Patel, T F Smith, M Espy...
https://pubmed.ncbi.nlm.nih.gov/8077384Detection of human cytomegalovirus in plasma of AIDS patients during acute visceral disease by DNA amplification.
S A Spector, R Merrill, D Wolf...
https://pubmed.ncbi.nlm.nih.gov/1328287