6-Month Study Evaluating an Antimicrobial Mouthrinse for Reducing Dental Plaque and Improving Gum Health

What this Trial Is About

This clinical trial evaluates the effectiveness of an antimicrobial mouthrinse in reducing established dental plaque and improving gum health in adults with gingivitis and dental plaque accumulation. The study focuses on measuring improvements in gum health using the Gingival Index and plaque reduction using the Plaque Index over a six-month period. Participants include adults aged 18 to 70 years who have at least 20 natural teeth and meet specific oral health criteria. Participants are randomly assigned to one of two groups the test group using a mouthrinse containing 0.0553% sodium fluoride, amine, and 0.2% zinc lactate dihydrate, or the control group using a mouthrinse with 0.0553% sodium fluoride only. Both groups will brush their teeth twice daily with provided toothpaste and toothbrush, then rinse with 15 ml of the assigned mouthrinse for 30 seconds. This routine continues for six months. Throughout the study, participants visit the clinic every three months after the baseline visit for reassessment. Researchers monitor gum health improvements and plaque levels using standardized indices. The study also includes safety monitoring and requires participants to maintain good general health and adhere to the treatment regimen. The total duration of participation is six months, with regular assessments to evaluate treatment effects.

6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health