Actively Recruiting
Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential
Led by Chinese University of Hong Kong · Updated on 2026-02-24
140
Participants Needed
1
Research Sites
934 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is to attain early recognition of the unstable plaques which have an imminent embolic risk in patients with intracranial atherosclerotic disease (IAD).
CONDITIONS
Official Title
Morphology of Advanced Symptomatic Cerebral Plaques With High Embolic Potential
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is 30 to 85 years of age, inclusive.
- For symptomatic group: acute infarct on MRI compatible with artery-to-artery embolism, intracranial atherosclerotic stenosis 60% or greater, and microembolic signals detected by TCD.
- No contraindications for proposed imaging tests.
- Understands the study purpose and has provided informed consent.
- For asymptomatic group: high-grade intracranial stenosis over 60% on MR angiography without infarct in the corresponding vascular territory and no microembolic signals on TCD.
You will not qualify if you...
- Stroke cause uncertain or unrelated to intracranial atherosclerosis, such as cardioembolism, Moyamoya disease, or small vessel disease.
- Tandem stenosis over 50% at proximal internal carotid artery.
- Bleeding risk conditions including active peptic ulcer, major systemic hemorrhage within 30 days, low platelets (under 100 x 10^9/L), or coagulopathy (INR over 1.5).
- Medical conditions preventing adherence to the study protocol or completion of the study.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
T
Thomas Wai Hong LEUNG, FRCP
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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