Actively Recruiting

Age: 18Years - 110Years
All Genders
NCT06563401

Mortality and Cardiovascular Diseases in Adult-onset Type 1 Diabetes

Led by Karolinska Institutet · Updated on 2025-04-03

900000

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Scarce evidence is available for prognosis in adult-onset type 1 diabetes (T1D). The aim of this study is to investigate the risk of all-cause mortality, cause-specific mortality, and incident CVD in adult-onset T1D, as compared to type 2 diabetes with comparable age at diagnosis and population controls. We will explore potential modifiable factors including lifestyle and clinical characteristics that contribute to T1D prognosis. In addition, we will estimate the life expectancy associated with different age at T1D diagnosis as compared to population controls. This study will be based on people with diabetes recorded in Swedish National Diabetes Registers, with linkages to other nationwide registers to retrieve data on lifestyle factors, biomarkers, treatment and outcome information.

CONDITIONS

Official Title

Mortality and Cardiovascular Diseases in Adult-onset Type 1 Diabetes

Who Can Participate

Age: 18Years - 110Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults diagnosed with type 1 diabetes at age 18 years or older between 2001 and 2020 from the National Diabetes Register
  • Adults diagnosed with type 2 diabetes at age 18 years or older between 2001 and 2020 from the National Diabetes Register
  • Type 1 diabetes cases matched by age, sex, and county to 50 population controls without diabetes from the Total Population Register
Not Eligible

You will not qualify if you...

  • People diagnosed with cancer in the digestive system within 1 year before their diabetes diagnosis
  • People with pancreatic cancer listed as their underlying cause of death

AI-Screening

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Trial Site Locations

Total: 1 location

1

Karolinska institute

Stockholm, Sweden, 17177

Actively Recruiting

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Research Team

S

Sofia Carlsson, phd

CONTACT

Y

Yuxia Wei, phd

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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