Study of a Digital Support Website for Adults Undergoing Stem Cell Transplant for Blood Cancer

What this Trial Is About

Researchers are evaluating if a special intervention website called Mosaic can improve patient-reported outcomes for adults with blood cancers undergoing allogeneic or autologous stem cell transplants. This study compares the intervention website to an educational website to see if it reduces psychological distress, cancer treatment-related distress, physical symptoms, and improves quality of life. The study also explores if benefits vary by patients language, initial distress levels, sex, race, ethnicity, and transplant type. Participants are randomly assigned to use either the intervention website or a control website throughout the study. Both websites provide coping and stress management training, educational content, and links to trusted resources in English and Spanish. The intervention website additionally offers experiential transplant information and supports skill practice. Participants can access their assigned website before and after transplant during the study period. Participants complete five assessments one before transplant and four follow-ups at 2, 4, 6, and 8 months post-transplant. Researchers measure changes in psychological distress, cancer treatment-related distress, symptoms, and health-related quality of life. The study monitors how patients use the websites and examines factors related to improvements. The entire study is expected to continue until 2030 with ongoing data collection and analysis.

Mosaic Trial for Stem Cell Transplant Recipients