Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID04632654

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain After Head and Neck Cancer Treatment

Led by University of Alabama at Birmingham · Updated on 2025-10-15

150

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a personalized physical activity program using motion exergames to help head and neck cancer patients manage fatigue and musculoskeletal pain during the first 6 months after their treatment. The study aims to compare this intervention, called PAfitME, to an attention control group receiving survivorship education and exergame equipment. The goals include measuring effects on fatigue, pain, functional status, and quality of life while exploring factors like physical activity self-efficacy and enjoyment that might influence results. The PAfitME intervention lasts 6 weeks and includes weekly sessions starting with an in-home setup, followed by FaceTime coaching calls and additional home visits. Participants receive personalized exergame prescriptions using platforms such as Wii Fit and Xbox Kinect, with progress adjustments during the program. The control group also receives exergame equipment and education from the National Cancer Institute but without the personalized coaching. Participants are monitored at the start and end of the 6-week period through patient-reported fatigue and pain scales, functional status tests including walk and grip strength tests, range of motion measurements, and quality of life questionnaires. The study involves 150 post-treatment head and neck cancer patients and uses statistical models to analyze outcomes. The total participation time is 6 weeks, with interventions delivered mainly at home and via telehealth.

CONDITIONS

Brief Title

A Motion Exergaming Approach for Symptom Management: HNC

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with head and neck cancer (tumor sites in the head and neck area)
  • 18 years or older
  • Able to understand English
  • Able to communicate
  • Karnofsky Performance Status score of 60% or higher
  • Cleared by their healthcare provider to resume low to moderate intensity physical activity
  • Have fatigue or pain of moderate severity (score of 4 or higher on a 0-10 scale)
Not Eligible

You will not qualify if you...

  • Currently hospitalized
  • In hospice care
  • Have a history of seizures or loss of consciousness
  • Cognitively impaired, defined as making 3 or more errors on a 6-item cognitive screener

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 6 weeks

Participants receive a personalized Physical Activity intervention with fitness graded Motion Exergames (PAfitME) or survivorship education with exergame equipment over 6 weeks.

7 weekly intervention sessions including home visits and FaceTime coaching calls

Trial Site Locations

Total: 1 location

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294

Actively Recruiting

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Research Team

H

Hsiao-Lan Wang

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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