Actively Recruiting

Phase Not Applicable
Age: 3Years - 17Years
All Genders
Healthy Volunteers
NCT05790668

Motivational Refinements for Facilitating Reinforcement Schedule Thinning

Led by Rutgers, The State University of New Jersey · Updated on 2025-07-24

30

Participants Needed

2

Research Sites

253 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Destructive behavior represents a comorbid condition of developmental disability for which risk increases with intellectual disability severity, communication deficits, and co-occurring autism spectrum disorder. Destructive behavior, such as self-injurious behavior and aggression, causes harm to the child and others and increases the risk for institutionalization, social isolation, physical restraint, medication overuse, and abuse. Clinicians have used functional analyses to identify the variables that reinforce destructive behavior and to develop effective, function-based treatments. Functional communication training (FCT) is an empirically supported, function-based treatment that decreases destructive behavior. Using FCT, the clinician teaches the child to use a functional communication response (FCR) to request the reinforcer maintaining destructive behavior, while placing destructive behavior on extinction. For example, if functional analysis results showed that attention reinforced destructive behavior, the clinician would provide attention when the child used the FCR ("Play with me, please") and would not provide attention for destructive behavior. Two limitations of FCT are that (a) schedules of reinforcement maintaining the FCR must often be thinned gradually to levels that are practical for caregivers to implement consistently in the home and in the community, and (b) this necessary process of reinforcement schedule thinning regularly causes destructive behavior to increase following initially effective treatment, a form of treatment relapse called resurgence. The current project aims to improve these limitations of FCT by (a) hastening the process of reinforcement schedule thinning by removing unnecessary schedule-thinning steps using the results of a progressive interval assessment and (b) mitigating the resurgence of destructive behavior by providing stimuli that highly compete with the reinforcer maintaining destructive behavior. The investigators will conduct a randomized clinical trial to evaluate the extent to which these two promising refinements to FCT improve the process of reinforcement schedule thinning, and an exploratory experiment will examine the interactive effects of these two approaches. This novel project has the potential to substantially improve standards of care guiding the treatment of severe destructive behavior and to improve the long-term outcomes for children and families afflicted by these debilitating behavior disorders.

CONDITIONS

Official Title

Motivational Refinements for Facilitating Reinforcement Schedule Thinning

Who Can Participate

Age: 3Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Boys and girls aged 3 to 17 years
  • Destructive behavior occurring at least 10 times daily despite previous treatment
  • Destructive behavior reinforced by social consequences
  • Stable protective supports for self-injurious behavior with no expected changes during the study
  • Stable psychoactive medication regimen for at least 10 half-lives or no medication
  • Stable educational plan and placement with no anticipated changes during treatment
Not Eligible

You will not qualify if you...

  • Not meeting all inclusion criteria
  • Currently receiving 15 or more hours per week of treatment for destructive behavior
  • Diagnosis of Rett syndrome or other degenerative conditions
  • Comorbid health condition or major mental disorder interfering with study participation
  • Self-injury during assessments posing risk of serious or permanent harm
  • Requiring changes to protective supports or medication, unless stable during participation

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Douglass Developmental Disabilities Center

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

2

Rutgers University Center for Autism Research, Education, and Services

Somerset, New Jersey, United States, 08873

Actively Recruiting

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Research Team

B

Brian D Greer, Ph.D.

CONTACT

D

Daniel R Mitteer, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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