Actively Recruiting
The Motor Activity - Subjective Energy (MASE) Project
Led by University of Bern · Updated on 2025-09-16
180
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
Sponsors
U
University of Bern
Lead Sponsor
U
University of Salzburg
Collaborating Sponsor
AI-Summary
What this Trial Is About
This approach utilizes accelerometry to measure NEA and electronic diaries for real-time psychological assessments, overcoming limitations of traditional methods such as retrospective bias and low ecological validity. Brief episodes of physical activity in daily life, which are distinctly different from structured exercise sessions, are generally linked to improved affective well-being. Notably, feelings of energy are particularly associated with incidental, unstructured, and non-exercise activities. Clinically, psychomotor retardation and diminished mood are key diagnostic features of MDD, with evidence suggesting that lower motor activity differentiates MDD patients from controls and that increased activity correlates with treatment response. In this context, the MASE project aims to design personalized BA interventions that focus on increasing NEA and, in turn, enhancing subjective energy levels to reduce depressive symptoms and prevent relapse.
CONDITIONS
Official Title
The Motor Activity - Subjective Energy (MASE) Project
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Sufficient knowledge of the German language
- Written informed consent
- Score > 15 on the Montgomery Asberg Depression rating scale (MADRS) for MDD group
- Remission within the past year and exhibit a MADRS score < 10 for at least one month for rMDD group
You will not qualify if you...
- Pregnancy at baseline
- Claustrophobia
- Pacemaker
- Artificial heart valves
- Active implants
- Other psychiatric disorders
- Acute suicidality
- Change of medication or psychotherapy during the intervention (not dosage but substance)
- For healthy participants: history of any mental health condition or first-degree relative with affective or psychotic disorder
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Bern
Bern, Switzerland, 3012
Actively Recruiting
Research Team
C
Claudio R. Nigg, Prof
CONTACT
L
Lea Nitzpon, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
3
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