Actively Recruiting
Motor-cognitive Performance in People With Multiple Sclerosis
Led by Karolinska Institutet · Updated on 2025-07-10
90
Participants Needed
1
Research Sites
183 weeks
Total Duration
On this page
Sponsors
K
Karolinska Institutet
Lead Sponsor
K
Karolinska University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Having a neurological disease such as multiple sclerosis (MS) leads to difficulties in balance and gait with or without concurrent performance of cognitive tasks, hindering activity performance and influencing the possibilities for an independent lifestyle. The investigators have adapted a previously developed balance training program to a highly challenging program specifically directed to MS (HiBalance-MS). This program was recently tested and found feasible in a pilot study. The investigators will now perform a randomized controlled trial in people with MS, in order to determine the effects of the program. The hypothesis is that progressively challenging balance exercise programs that are specific to the balance control domains affected by MS will be effective to improve balance control, walking, motor-cognitive performance, activity performance and health related quality of life.
CONDITIONS
Official Title
Motor-cognitive Performance in People With Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of multiple sclerosis according to McDonald criteria
- Expanded Disability Status Scale score between 2.0 and 5.5
- Ability to walk 100 meters without aid
- Mini Balance Evaluation Systems Test score less than 25
- Age between 18 and 65 years
You will not qualify if you...
- Cognitive impairment with Montreal Cognitive Assessment score below 21
- Presence of other conditions that substantially affect balance
- MS relapse or change in disease-modifying treatment within the past 8 weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Stockholm, Stockholm County, Sweden, 17177
Actively Recruiting
Research Team
C
Compliance Office Karolinska Institutet
CONTACT
E
Erika Franzén, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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