Actively Recruiting
Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2026-04-29
30
Participants Needed
1
Research Sites
181 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
With this project, the study group wants to investigate whether a postoperative navigated transcranial magnetic stimulation (nTMS) motor map can improve stereotactic radiosurgery (SRS) planning in patients who underwent resection for a brain metastasis near the primary motor cortex. Specifically, the map could allow for more precise location of motor eloquent tissue, thereby minimizing the radiation dose on these areas while preserving high radiation dose on target tissue (i.e. tumor cells).
CONDITIONS
Official Title
Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Age 18 years or older
- Brain metastasis located within or adjacent to the primary motor cortex (within 10 mm)
- Tumor has been surgically removed
- Planned postresection stereotactic radiosurgery at Inselspital Bern
You will not qualify if you...
- Contraindications to TMS such as cochlear implant, other metallic or electrical implants (excluding teeth and post craniotomy), Meniere's disease, pacemaker, deep brain stimulation electrodes, refractory convulsions, specialist-diagnosed depression, or psychosis
- Previous cerebral radiation therapy in the affected precentral gyrus or planned SRS area
- Planned whole brain radiotherapy
- Presence of a second lesion within 2 cm on the same side in the primary motor cortex
- Infection or wound healing problems within two weeks before inclusion
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hostpital Bern, Department of Neurosurgery Bern
Bern, Switzerland, 3010
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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