Actively Recruiting

All Genders
NCT04635891

Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

Led by University of Kansas Medical Center · Updated on 2026-05-07

450

Participants Needed

21

Research Sites

367 weeks

Total Duration

On this page

Sponsors

U

University of Kansas Medical Center

Lead Sponsor

F

FSHD Society, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary goal of this proposal is to collect motor and functional outcomes specific to FSHD over time. By collecting measures specific to FSHD, this will help ensure the best level of clinical care is being provided. Also, the hope is to speed up drug development by gaining a better understanding of how having FSHD impacts motor function and other health outcomes (i.e. breathing, wheelchair use, etc.) and how big a change in motor function would be clinically meaningful to those with FSHD. Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) will have approximately 450 FSHD participants followed for a minimum of 3 years. A subset of MOVE FSHD participants, approximately 200, will participate in the MOVE+ sub-study which includes whole body MRI and reachable workspace, as well as optional muscle biopsy and wearable device (US participants only).

CONDITIONS

Official Title

Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Genetically confirmed FSHD (types 1 or 2) or clinical diagnosis of FSHD with characteristic findings on exam and an affected parent or offspring.
Not Eligible

You will not qualify if you...

  • Unwilling or unable to provide informed consent.
  • Any other medical condition which in the opinion of the investigator would interfere with study participation.

AI-Screening

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Trial Site Locations

Total: 21 locations

1

David Geffen School of Medicine at UCLA

Los Angeles, California, United States, 90095

Actively Recruiting

2

Neuromuscular Disorders Program at Stanford University School of Medicine

Stanford, California, United States, 94306

Actively Recruiting

3

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

4

Univeristy of Florida Gainesville

Gainesville, Florida, United States, 32608

Actively Recruiting

5

University of Iowa

Iowa City, Iowa, United States, 52242

Actively Recruiting

6

Univeristy of Kansas Medical Center

Kansas City, Kansas, United States, 66160

Actively Recruiting

7

Kennedy Krieger Institute

Baltimore, Maryland, United States, 21205

Actively Recruiting

8

University of Rochester Medical Center

Rochester, New York, United States, 14642

Actively Recruiting

9

Duke University - Lenox Baker Children's Hospital

Durham, North Carolina, United States, 27705

Actively Recruiting

10

The Ohio State University Medical Center

Columbus, Ohio, United States, 43221

Actively Recruiting

11

Austin Neuromuscular Center

Austin, Texas, United States, 78759

Actively Recruiting

12

Univeristy of Texas Southwestern Medical Center

Dallas, Texas, United States, 75390

Actively Recruiting

13

University of Texas Health San Antonio

San Antonio, Texas, United States, 78229

Not Yet Recruiting

14

University of Utah

Salt Lake City, Utah, United States, 84132

Actively Recruiting

15

Virginia Commonwealth University

Richmond, Virginia, United States, 23219

Actively Recruiting

16

University of Washington Medical Center

Seattle, Washington, United States, 98195

Actively Recruiting

17

University of Sao Paulo

São Paulo, Brazil

Actively Recruiting

18

University of Calgary

Calgary, Alberta, Canada, T2N1N4

Not Yet Recruiting

19

Ottawa Hospital Research Institute

Ottawa, Ontario, Canada, K1y 4e9

Actively Recruiting

20

University of McGill

Montreal, Quebec, Canada, H3A 2B4

Not Yet Recruiting

21

Sheffield Teaching Hospital

Sheffield, South Yorkshire, United Kingdom, S10 2JF

Actively Recruiting

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Research Team

M

Michaela Walker, MPH

CONTACT

L

Leann Lewis, MSGC

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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