Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06670001

MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

Led by University of Pennsylvania · Updated on 2025-09-22

270

Participants Needed

1

Research Sites

199 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a three-arm, randomized, controlled trial to test the effectiveness of gamification plus a social incentive - either social support or competition - to increase adherence to physical activity among individuals with HFpEF. There will be a 2-week run-in period to obtain baseline measures of physical activity, followed by a 6-month intervention period and then a 3-month follow-up period.

CONDITIONS

Official Title

MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Diagnosis of heart failure with preserved ejection fraction
  • Ejection fraction of 50% or higher
  • Meet at least one of the following: history of hospitalization for HFpEF, BNP > 75 pg/mL (or > 225 pg/mL if atrial fibrillation), H2FPEF score of 5 or more, or elevated pulmonary capillary wedge pressure (≥ 15 mm Hg at rest or ≥ 25 mm Hg with exercise)
  • Own a smartphone or tablet with internet capability
  • Able to read English
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Currently participating in another interventional physical activity study
  • Medical conditions preventing walking without assistance (except cane) or participation in exercise
  • Infeasibility or safety concerns regarding a 9-month physical activity program
  • Scheduled cardiovascular procedures soon (e.g., stent or surgery)
  • High physical activity level (> 7500 steps/day) at baseline
  • Very low physical activity level (< 1000 steps/day) at baseline
  • Dementia
  • End-stage renal disease on dialysis
  • Cirrhosis
  • Cardiac surgery or valve replacement within the past year
  • Severe aortic stenosis or severe mitral stenosis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

S

Samantha Coratti

CONTACT

C

Chinyere Anucha

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

3

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