Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05842603

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

Led by Massachusetts General Hospital · Updated on 2025-09-25

30

Participants Needed

3

Research Sites

148 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to see if patients with myeloproliferative disorders are able to successfully complete the Cardiac Lifestyle Program(CLP). The goal of the CLP is to teach patients how to become more active and eat healthier foods. The name of the intervention used in this research study is: Cardiac Lifestyle Program (a 12-week, tailored nutrition and physical activity program)

CONDITIONS

Official Title

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Diagnosed with a myeloproliferative neoplasm (MPN) by WHO 2016 criteria, including essential thrombocythemia, polycythemia vera, prefibrotic myelofibrosis, myelofibrosis, or MPN not otherwise specified
  • For myelofibrosis patients, only those with low or intermediate-1 risk by the Dynamic International Prognostic Scoring System (DIPSS) are eligible
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0-1
  • Must have at least one cardiovascular risk factor such as BMI over 25 kg/m2, hypertension, high cholesterol, diabetes or pre-diabetes, metabolic syndrome, or a history of cardiovascular disease, transient ischemic attack, stroke, or peripheral vascular disease; patients without cardiovascular risk factors require prior approval from the principal investigator
Not Eligible

You will not qualify if you...

  • Myelofibrosis patients with intermediate-2 or high-risk disease by DIPSS
  • Eastern Cooperative Oncology Group (ECOG) performance status greater than 2
  • Any injury or medical condition that prevents safe participation in exercise, as determined by the treating physician

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
3
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Trial Site Locations

Total: 3 locations

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02215

Actively Recruiting

2

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Not Yet Recruiting

3

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

G

Gabriela Hobbs, MD

CONTACT

G

Gabriella Hobbs, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients | DecenTrialz