Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06891625

Movement Performance in Persons With Chronic Back Pain

Led by Karolinska Institutet · Updated on 2025-07-14

40

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

Sponsors

K

Karolinska Institutet

Lead Sponsor

S

Stiftelsen Rönnbäret

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance, gait, active trunk mobility and pain-intensity in persons with chronic non-specific back pain. The main question this study aims to answer is: What are the immediate and measurable effects of SMT and ET on work movements, gait, active trunk mobility and pain-intensity in people with chronic non-specific back pain, compared with and in combination with open-label placebo treatment (OP)? The investigators hypothesize that the participants, after SMT and ET, will perform the lifting task faster, and use more range of motion in most of the joints. They also believe that a greater range of motion is used during gait and that the active ROM in the back is increased, while the pain intensity scores decrease after these interventions. The investigators hypothesize that the control intervention (OLP) could be effective as an add-on intervention, but not as a single intervention. All participants will receive all three interventions SMT, ET and OLP and to study the immediate effects, the participants will be asked: * to lift a box with two different weights * to walk straight forward with and without a cognitive dual task * perform two clinical tests of active range of motion ( * rate the intensity of their pain "right now" * rank the treatment effects of these three treatment methods

CONDITIONS

Official Title

Movement Performance in Persons With Chronic Back Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Persons with continuous or recurring back pain lasting longer than 3 months affecting the spine from Th1 to the inferior gluteal fold
  • Age over 18 years
  • Able to speak and understand Scandinavian or English
Not Eligible

You will not qualify if you...

  • Presence of red flags indicating serious back conditions
  • Specific back problems such as rheumatic inflammatory joint or back diseases
  • Fractures
  • Diagnosed hip osteoarthritis
  • Fibromyalgia
  • Neurological co-morbidities

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Karolinska Institutet

Huddinge, Sweden, 141 83

Actively Recruiting

Loading map...

Research Team

W

Wilhelmus JA Grooten, associated professor

CONTACT

E

Erika Franzen, prof

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here