Actively Recruiting
Movement Performance in Persons With Chronic Back Pain
Led by Karolinska Institutet · Updated on 2025-07-14
40
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
K
Karolinska Institutet
Lead Sponsor
S
Stiftelsen Rönnbäret
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance, gait, active trunk mobility and pain-intensity in persons with chronic non-specific back pain. The main question this study aims to answer is: What are the immediate and measurable effects of SMT and ET on work movements, gait, active trunk mobility and pain-intensity in people with chronic non-specific back pain, compared with and in combination with open-label placebo treatment (OP)? The investigators hypothesize that the participants, after SMT and ET, will perform the lifting task faster, and use more range of motion in most of the joints. They also believe that a greater range of motion is used during gait and that the active ROM in the back is increased, while the pain intensity scores decrease after these interventions. The investigators hypothesize that the control intervention (OLP) could be effective as an add-on intervention, but not as a single intervention. All participants will receive all three interventions SMT, ET and OLP and to study the immediate effects, the participants will be asked: * to lift a box with two different weights * to walk straight forward with and without a cognitive dual task * perform two clinical tests of active range of motion ( * rate the intensity of their pain "right now" * rank the treatment effects of these three treatment methods
CONDITIONS
Official Title
Movement Performance in Persons With Chronic Back Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Persons with continuous or recurring back pain lasting longer than 3 months affecting the spine from Th1 to the inferior gluteal fold
- Age over 18 years
- Able to speak and understand Scandinavian or English
You will not qualify if you...
- Presence of red flags indicating serious back conditions
- Specific back problems such as rheumatic inflammatory joint or back diseases
- Fractures
- Diagnosed hip osteoarthritis
- Fibromyalgia
- Neurological co-morbidities
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Huddinge, Sweden, 141 83
Actively Recruiting
Research Team
W
Wilhelmus JA Grooten, associated professor
CONTACT
E
Erika Franzen, prof
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
3
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