Actively Recruiting
Mpox Comprehensive Assessment for Responsive Immunisation in Emergency Outbreaks
Led by University of Birmingham · Updated on 2025-03-20
650
Participants Needed
1
Research Sites
94 weeks
Total Duration
On this page
Sponsors
U
University of Birmingham
Lead Sponsor
R
Rwanda Biomedical Centre
Collaborating Sponsor
AI-Summary
What this Trial Is About
The MPXV CARE study principally aims to use clinical and epidemiology data to target specific individuals willing and able to provide appropriate and proportionate biological samples to develop novel immune diagnostics that support models of disease burden and future vaccine utilisation.
CONDITIONS
Official Title
Mpox Comprehensive Assessment for Responsive Immunisation in Emergency Outbreaks
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy males and females aged 5 to 80 years who can provide informed consent and comply with study requirements
- For suspected exposure group: live in or near an area with Mpox transmission or be a close contact of a confirmed Mpox case
- For post-exposure/vaccinated group: prior confirmed Mpox infection or previous smallpox/MVA vaccination and fully recovered from infection
- For control group: asymptomatic with no known exposure to Mpox
You will not qualify if you...
- Unable or unwilling to provide informed consent or follow study procedures
- History of immune system disorder that could affect study results
- Significant bleeding disorder
- Pregnant or breastfeeding females
- For suspected exposure group: known prior Mpox infection, current Mpox symptoms, or known Mpox exposure in the last month
- For post-exposure/vaccinated group: ongoing Mpox symptoms indicating incomplete recovery
- For control group: symptoms of Mpox or known Mpox exposure in the last month
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rwanda Biomedical Center
Kigali, Rwanda, P.O. Box 7162
Actively Recruiting
Research Team
S
Shema Hugor
CONTACT
K
Karishma Gokani
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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