Actively Recruiting
MRD-positive AML Clinical Study
Led by Institute of Hematology & Blood Diseases Hospital, China · Updated on 2025-08-20
120
Participants Needed
1
Research Sites
207 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial is a platform-type clinical study intended to investigate the efficacy and safety of MRD-positive acute myeloid leukemia patients after comprehensive treatment, which includes but is not limited to the following drugs and protocols: Chemotherapy, small molecule targeted drugs, demethylation drugs, liposome drugs and the combination of these drugs to form a combination of treatment regimen, the specific treatment regimen will be updated according to the results of this trial and the latest research progress at home and abroad.
CONDITIONS
Official Title
MRD-positive AML Clinical Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with AML (non-M3) according to WHO (2016) standards
- In morphological complete remission
- MRD-positive by bone marrow flow cytometry, PCR for NPM1 mutations, PCR for fusion genes (RUNX1-RUNX1T1, CBFB-MYH11, DEK-NUP214), or NGS detection of FLT3 mutation
- Age 14 years or older, male or female
- Informed consent signed by patient, immediate family member, or legal guardian before study procedures
You will not qualify if you...
- Planning to undergo hematopoietic stem cell transplantation within 4 weeks
- Diagnosed with acute promyelocytic leukemia (APL)
- Deemed unsuitable for inclusion by the researchers
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Blood Diseases Hospital
Tianjin, Tianjin Municipality, China, 300020
Actively Recruiting
Research Team
H
Hui Wei, Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
7
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here