Actively Recruiting
MRE for Diagnosis of Pancreatic Masses
Led by Yu Shi · Updated on 2026-02-13
200
Participants Needed
1
Research Sites
346 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors facilitates risk stratification and prospective assessment in clinical trials. The extracellular matrix (ECM) surrounding PDAC often exhibits a large number of interstitial fibrosis, which is closely related to the formation, development and metastasis of PDAC. High order three-dimensional MR elastography (3D-MRE) allows non-invasive measurements of sheer stiffness in normal pancreas and pancreatic lesions. However, there are no reports about the application of MRE imaging biomarkers to predict the prognosis of PDAC at home and abroad.
CONDITIONS
Official Title
MRE for Diagnosis of Pancreatic Masses
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Granting of written informed consent
- Age 18 years or older
- No history of extrapancreatic malignancy
- No preoperative biliary drainage
- Definitive histologic evidence of PDAC in excisional biopsy
- Survival of at least three months postoperatively or six months of follow-up
You will not qualify if you...
- Inability to re-review tissue specimens
- Unacceptable MRE parameter estimates, including invalid wave data, inconsistent breath-holding, intolerable pain, or MRE hardware disconnection
- Tumor diameter smaller than 1.0 cm
- Withdrawal or dropout during follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shengjing hospital of china medical university
Shenyang, Liaoning, China, 110004
Actively Recruiting
Research Team
Y
Yu Shi, MD.PhD.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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