Actively Recruiting

Age: 18Years +
All Genders
NCT03999138

MRI Assessment of Pulmonary Edema in Acute Heart Failure

Led by University of Alberta · Updated on 2026-05-08

300

Participants Needed

2

Research Sites

469 weeks

Total Duration

On this page

Sponsors

U

University of Alberta

Lead Sponsor

C

Canadian Institutes of Health Research (CIHR)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or "increased lung water") in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.

CONDITIONS

Official Title

MRI Assessment of Pulmonary Edema in Acute Heart Failure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older and willing/able to provide informed consent
  • Patients being treated for acute heart failure, including those with reduced or preserved ejection fraction
  • Patients receiving medical therapy for pulmonary edema with oral or IV diuretics
  • Patients identified within 48 hours of starting or increasing diuretic therapy during emergency or hospital care
Not Eligible

You will not qualify if you...

  • Contraindication to MRI
  • Patient too critically ill or unstable for transport to MRI scanner within required scanning window
  • Moderate to severe dementia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University of Alberta

Edmonton, Alberta, Canada

Active, Not Recruiting

2

University of Ottawa Heart Institute

Ottawa, Ontario, Canada

Actively Recruiting

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Research Team

I

Ian Paterson, MD

CONTACT

P

Poppy MacPhee, RN, BScN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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