Actively Recruiting
MRI-Based Prediction of Dienogest Response in Endometriosis
Led by Chungnam National University Sejong Hospital · Updated on 2026-03-03
48
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this prospective observational study is to learn whether magnetic resonance imaging (MRI) findings can help predict treatment response to dienogest in women with endometriosis. Endometriosis is a common gynecologic condition that can cause chronic pelvic pain and negatively affect quality of life. Although dienogest is widely used as a standard medical treatment, individual responses to treatment vary. The main questions this study aims to answer are: * Whether baseline MRI characteristics of endometriotic lesions are associated with improvement in pelvic pain after dienogest treatment. * Whether MRI findings can help identify patients who are more likely to benefit from dienogest therapy. Participants diagnosed with endometriosis who are prescribed dienogest as part of their routine clinical care will be enrolled. This study does not assign any investigational intervention. Participants will undergo standard clinical follow-up, including pelvic pain assessment using visual analog scale (VAS) scores, quality of life questionnaires, and routine MRI examinations. Clinical and imaging data will be collected prospectively and analyzed to explore imaging predictors of treatment response.
CONDITIONS
Official Title
MRI-Based Prediction of Dienogest Response in Endometriosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female participants who have received a full explanation of the study and have provided written informed consent
- Women aged 19 to 45 years who have been diagnosed with endometriosis by a board-certified obstetrician-gynecologist
- Patients who have not received any hormonal treatment within the previous 3 months
- Patients who have never been treated with dienogest
You will not qualify if you...
- Patients with a history of treatment with dienogest
- Patients with contraindications to dienogest
- Patients who are unable to undergo magnetic resonance imaging (MRI) (e.g., presence of metallic implants)
- Patients who are currently pregnant or planning pregnancy within the next 6 months
- Patients with poor general medical condition, as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Sejong Chungnam National University Hospital
Sejong, Sejong Special Self-Governing City, South Korea, 30099
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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