Actively Recruiting

Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT02170155

MRI-changes in Morphometry and Cerebro Spinale Fluid (CSF) Flow in Spinal Cord Disorders

Led by University of Zurich · Updated on 2025-12-22

350

Participants Needed

1

Research Sites

730 weeks

Total Duration

On this page

Sponsors

U

University of Zurich

Lead Sponsor

F

Foundation Wings For Life

Collaborating Sponsor

AI-Summary

What this Trial Is About

Understanding the onset and progression of spinal cord disorders is an important aim in clinical neurology. An early diagnosis with consequent therapy might prevent the progression of disability. Therefore, we aim to determine structural and dynamic changes in the microstructure of the spinal cord and CSF, and to explore the relationships between the MRI parameters, clinical disability, and electrophysiology. In some patients that undergo decompressive surgery CSF pressure will be measured invasive perioperative for 24h to find out if functional limitations and structural changes correlate with the spinal pressure and the spinal perfusion when the spinal cord is damaged.

CONDITIONS

Official Title

MRI-changes in Morphometry and Cerebro Spinale Fluid (CSF) Flow in Spinal Cord Disorders

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Cervical injury
  • Informed consent
  • Age 18-80
  • Cervical spondylotic myelopathy (CSM)
Not Eligible

You will not qualify if you...

  • Other neurological or psychiatric disorders
  • History of seizures
  • MRI incompatibility
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Zurich, Balgrist University Hospital

Zurich, Canton of Zurich, Switzerland, 8008

Actively Recruiting

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Research Team

P

Patrick Freund, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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