Actively Recruiting
Can MRI of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour
Led by Nova Scotia Health Authority · Updated on 2024-08-21
60
Participants Needed
1
Research Sites
190 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prostate cancer is the most common cancer diagnosed in men in Canada. Magnetic resonance imaging (MRI) may become a valuable tool to non-invasively identify prostate cancer and assess its biological aggressiveness, which in turn will help doctors make better decisions about how to treat an individual patient's prostate cancer. Despite the promise of MRI for detecting and characterizing prostate cancer, there are several recognized limitations and challenges. These include lack of standardized interpretation and reporting of prostate MRI exams. The investigators propose to validate and improve a computer program computerized prediction tool that will use information from MR images to inform us how aggressive a prostate cancer is. The hypothesis is that this computer-aided approach will increase the reproducibility and accuracy of MRI in predicting the tumor biology information about the imaged prostate cancer.
CONDITIONS
Official Title
Can MRI of the Prostate Combined With a Radiomics Evaluation Determine the Invasive Capacity of a Tumour
Who Can Participate
Eligibility Criteria
You may qualify if you...
- MRI scan performed on a 3T MRI machine at the Halifax Infirmary Building within 5 weeks of study enrollment
- MRI shows a detectable nodule that matches biopsy-confirmed prostate cancer
- MRI includes T1+contrast, T2, and ADC axial images of the prostate
- Prostate biopsy done within 2 months of first MRI and within 3 months of enrollment
- Biopsy confirms prostate cancer and assesses at least 12 cores
- At least one biopsy core involved with prostate cancer matches the MRI nodule
You will not qualify if you...
- Past prostate procedures that change prostate structure
- Changes in physiological testosterone levels
- Unable to position self consistently for MRI scan
- Patient factors causing significant MRI scan artifacts
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Victoria General Hospital
Halifax, Nova Scotia, Canada, B3H1V7
Actively Recruiting
Research Team
B
Beverly A Lieuwen, BSc
CONTACT
D
Dr. Michael Kucharczyk
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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