Study Using MRI and Ultrasound to Understand Muscle, Bone, and Joint Function in People Aged 5 to 95

What this Trial Is About

Researchers are studying how muscles, tendons, and bones work together to produce motion by using magnetic resonance imaging MRI and ultrasound. The study aims to develop advanced tools to measure and visualize three-dimensional joint anatomy and tissue dynamics, focusing on both normal and impaired musculoskeletal function. This research seeks to improve diagnosis and treatment methods for movement disorders by assessing joint structure and function in healthy volunteers and those with musculoskeletal impairments. Participants include individuals aged 5 to 95 years, with or without musculoskeletal impairments. The study uses MRI, where participants lie inside a scanner for up to three hours while moving specific joints briefly. Ultrasound imaging is also used to assess soft tissues like muscles and tendons. These imaging techniques are combined and analyzed to create detailed 3D digital images of moving joints, helping to understand joint contact patterns and tissue loads during movement. During the study, participants undergo static and dynamic MRI and ultrasound imaging sessions. They may wear earplugs to reduce scanner noise and communicate with staff throughout the procedure. Researchers measure tissue velocity, bone and muscle movement, and ultrasound images of the knee joint muscles and bones. The information collected helps evaluate joint function variability and supports future clinical applications. The total participation time varies depending on imaging sessions and assessments required.

MRI Study of Musculoskeletal Function