Actively Recruiting
MRSA Decolonization in Complicated Carriage
Led by Leiden University Medical Center · Updated on 2025-03-06
211
Participants Needed
1
Research Sites
301 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Multicenter open-label cluster randomized controlled trial determining the superiority of doxycycline-rifampicin compared to trimethoprim-rifampicin for the decolonization treatment of complicated MRSA carriership.
CONDITIONS
Official Title
MRSA Decolonization in Complicated Carriage
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6518 years
- Complicated MRSA carriership defined by any of the following: MRSA at sites other than the nose, active MRSA infection, mupirocin resistance in vitro, active skin lesions, presence of foreign material connecting internal body site to outside, or previous failure of decolonization treatment
- Ability to provide informed consent for the use of their data
You will not qualify if you...
- Presence of any intravenous access, urinary catheters, or drains
- Failure of previous decolonization attempt for complicated MRSA carriage
- Allergy or contraindication to doxycycline, rifampicin, or trimethoprim
- Previous participation in this study
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
LUMC
Leiden, Netherlands
Actively Recruiting
Research Team
A
Annette Westgeest, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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