Actively Recruiting

Age: 18Years +
All Genders
NCT05663385

Mucograft Seal in ARP Follow-up

Led by Erasmus Medical Center · Updated on 2025-08-12

75

Participants Needed

1

Research Sites

76 weeks

Total Duration

On this page

Sponsors

E

Erasmus Medical Center

Lead Sponsor

I

Institut Straumann AG

Collaborating Sponsor

AI-Summary

What this Trial Is About

Rationale: Early implant placement with alveolar ridge preservation (ARP) using either a collagen matrix or a palatal graft rendered similar esthetic, clinical and PROMs to early implant placement without ARP, up to 1 year after functional loading. Objective: The aim of this study is to evaluate esthetic and clinical outcomes and patient satisfaction following single-tooth replacement in the anterior maxilla in patients treated with a xenograft and a collagen matrix or a free connective tissue graft versus spontaneous healing 5 years after loading Study design: prospective observational study with 5-year follow-up Intervention (if applicable): not applicable Main study parameters/endpoints: Comparison of the level of the buccal marginal gingiva (midfacial mucosa level) between ARP versus spontaneous healing Secondary parameters/endpoint: Peri-implant esthetic score (PES) and white esthetic score (WES), complications, implant survival; and success, Plaque Index, Modified bleeding index, Gingival Index, Probing Depth, PROMs, bone and soft tissue volumetric dimensional changes.

CONDITIONS

Official Title

Mucograft Seal in ARP Follow-up

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients previously included in the above mentioned RCT.
Not Eligible

You will not qualify if you...

  • Patients treated with radiotherapy during follow-up in the head-and-neck region or current chemotherapy
  • Disability (mental and/or physical) to maintain basic oral hygiene procedures

AI-Screening

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Trial Site Locations

Total: 1 location

1

Erasmus Mc

Rotterdam, Netherlands, 3015gd

Actively Recruiting

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Research Team

J

Justin Pijpe, MD DDS PhD MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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