Actively Recruiting

Age: 18Years +
All Genders
NCT06287788

A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis

Led by Nanfang Hospital, Southern Medical University · Updated on 2024-03-01

240

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The performance of the predictive models for severe oropharyngeal mucositis established using current oral mucosal contouring method was unsatisfactory in nasopharyngeal carcinoma (NPC). Whereas the predictive model of a mucosal contouring method based on swallowing-induced breakthrough pain exhibited better overall performance. The aim of this prospective, multicenter, observational study was to further explore the predictive efficacy of this mucosal delineation method for radiation-induced oropharyngeal mucositis in NPC.

CONDITIONS

Official Title

A Mucosal Contouring Method Based on Swallowing-induced Breakthrough Pain for Radiation-induced Oropharyngeal Mucositis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide informed written consent.
  • Be 18 years of age or older.
  • Have histologically confirmed nasopharyngeal carcinoma.
  • Currently be undergoing radical radiotherapy or chemoradiotherapy.
  • Have complete and continuous records of oral or oropharyngeal mucositis grading and self-reported swallowing-induced breakthrough pain.
Not Eligible

You will not qualify if you...

  • Have poor oral hygiene, untreated dental or periodontal diseases, or metal dental restorations.
  • Have untreated or unresolved unstable heart diseases requiring treatment.
  • Have poorly controlled diabetes mellitus.
  • Have a body mass index (BMI) less than 18.5.
  • Be deemed unsuitable to participate by the researchers.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Southern Medical University

Guangzhou, Guangdong, China, 510515

Actively Recruiting

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Research Team

J

Jian Guan, Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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