Actively Recruiting
Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
Led by University of Erlangen-Nürnberg Medical School · Updated on 2024-07-05
115
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aim of the study is to improve the diagnosis of food allergy and hypersensitivity. Intestinal homogenates will be used to determine total IgE, specific IgE, tryptase, histamine and inflammation parameters (IFNgamma, TNFalpha). These data will be correlated with serum values and disease status. In addition, organoids from duodenal tissue will be isolated and cultured in vitro and stimulated with the major food allergens. The gene and protein expression will be checked to identify relevant biomarkers.
CONDITIONS
Official Title
Mucosal IgE to Improve Diagnosis of Food Allergy and Food Hypersensitivity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provided informed consent
- Have suspected food allergy or hypersensitivity
- Healthy controls indicated for endoscopic diagnostics, such as family history of tumors or to exclude gastritis
You will not qualify if you...
- Currently pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg
Erlangen, Germany, 91052
Actively Recruiting
Research Team
Y
Yurdagül Zopf, Prof
CONTACT
W
Walburga Dieterich, Dr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here