Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06424119

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

Led by Pritikin ICR · Updated on 2024-05-21

450

Participants Needed

3

Research Sites

192 weeks

Total Duration

On this page

Sponsors

P

Pritikin ICR

Lead Sponsor

B

Ballad Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this prospective study is to evaluate whether the Intensive Cardiac Rehabilitation (ICR) program provides incremental benefits over the Traditional Cardiac Rehabilitation (TCR) program, defined by readmission costs. The study aims to confirm: * That ICR is associated with better outcomes than TCR, defined as lower readmission costs, lower incidence of major adverse cardiovascular events (MACE), and improvement in biomarkers, epigenetic markers, and inflammatory markers. * The addition of food to the ICR program will further improve these outcomes. ICR-eligible participants * Will be randomized into one of three groups: (1) ICR 72 session program with home-delivered C2life® supplied food, (2) ICR 72 session without C2life® supplied food, or (3) TCR 36 session program without C2life supplied food * Biometric measurements and laboratory measurements will be performed at entry into the rehab intervention, discharge from rehab intervention, and at 6 months after discharge. * Epigenetic measurements will be performed at admission and discharge from the rehab intervention

CONDITIONS

Official Title

Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients eligible for an Intensive Cardiac Rehabilitation (ICR) Program at each of the three study sites outline below, stratified by one of the following qualifying cardiovascular events, including myocardial infarction (STEMI and NSTEMI), angioplasty and stents, coronary artery bypass, surgical or percutaneous valve repair or replacement, and stable congestive heart failure with reduced ejection fraction of 35% or less.
Not Eligible

You will not qualify if you...

  • Anticipated life expectancy of under 2 years
  • Any co-morbidity that would limit participation in the study.

AI-Screening

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Trial Site Locations

Total: 3 locations

1

Trinity Health Ann Arbor

Ypsilanti, Michigan, United States, 48197

Actively Recruiting

2

Mission Health

Asheville, North Carolina, United States, 28803

Actively Recruiting

3

Ballad CVA Heart Institute

Kingsport, Tennessee, United States, 37660

Not Yet Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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