Actively Recruiting
Multi-centred Clinico-genetic Study of Actinic Prurigo in Thailand
Led by Chulalongkorn University · Updated on 2026-05-12
47
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
Sponsors
C
Chulalongkorn University
Lead Sponsor
H
Health Systems Research Institute,Thailand
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research project investigates the clinical and genetic associations of Actinic Prurigo (AP) in the Thai population. As a rare chronic photodermatosis, AP has been observed to occur more frequently in individuals with certain genetic predispositions, particularly specific Human Leukocyte Antigen (HLA) types. Previous studies have suggested variations in clinical presentation and HLA allele distributions between Asian and Western populations. The primary aim is to explore the relationship between clinical manifestations of AP and genetic profiles, including HLA typing, among Thai individuals. Additionally, the study seeks to examine whether different HLA types are associated with varying responses to treatment. The study design is a cross-sectional comparative study, involving both AP patients and age-matched healthy controls. Given the rarity of the condition, patient recruitment will be conducted across four collaborating institutions: King Chulalongkorn Memorial Hospital Siriraj Hospital Institute of Dermatology
CONDITIONS
Official Title
Multi-centred Clinico-genetic Study of Actinic Prurigo in Thailand
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Thai ethnicity
- Diagnosed with Actinic Prurigo according to study criteria
- Mentally competent, able to communicate, and able to read Thai
- Participants on Thalidomide must use two contraception methods starting at least 4 weeks before treatment and continuing during treatment and for 4 weeks after stopping
You will not qualify if you...
- History or signs of other photodermatoses such as Lupus erythematosus, Porphyria, or Polymorphous Light Eruption
- Elevated Epstein-Barr Virus viral load detected by blood test
- Low Minimal Erythema Dose to UVB radiation as the only abnormal finding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Medicine Chulalongkorn University
Bangkok, Thailand
Actively Recruiting
Research Team
E
Einapak Boontaveeyuwat, MD
CONTACT
K
Kittima Leklad
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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