Actively Recruiting
A Multi-dimensional Evaluation of the Effects of Linear Accelerator X-ray Irradiation on Red Blood Cells
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2026-02-17
20
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate the effects of linear accelerator X-ray irradiation on the structure, mechanics and functional characteristics of red blood cells recovered from patients with malignant tumors during surgery. A red blood cell damage evaluation system based on multiple-dimensional indicators is established. Through atomic force microscopy, microfluidic chips and biochemical detection methods, the changes in red blood cell membrane structure, deformability and oxygen-carrying capacity under different irradiation doses are systematically evaluated. The dose-effect relationship between irradiation dose and red blood cell damage degree is clarified, providing experimental evidence for the safe dose of irradiation processing of autologous blood during surgery.
CONDITIONS
Official Title
A Multi-dimensional Evaluation of the Effects of Linear Accelerator X-ray Irradiation on Red Blood Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled for elective surgery for malignant tumors
- Age between 18 and 65 years old
- Expected surgical blood loss of 500 milliliters or more
You will not qualify if you...
- Disorders of red blood cell production such as aplastic anemia, megaloblastic anemia, iron deficiency anemia, leukemia, or myelofibrosis
- Diseases causing increased red blood cell destruction such as hereditary spherocytosis, paroxysmal nocturnal hemoglobinuria, thalassemia, or glucose-6-phosphate dehydrogenase deficiency
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital, School of Medicine, Zhejiang University,anesthesiology department,
Hangzhou, Zhejiang, China, 310009
Actively Recruiting
Research Team
F
Fengjiang Zhang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here