Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
NCT07488091

Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana

Led by University of Ghana Medical School · Updated on 2026-03-23

198

Participants Needed

1

Research Sites

111 weeks

Total Duration

On this page

Sponsors

U

University of Ghana Medical School

Lead Sponsor

V

Vanderbilt University Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to determine the feasibility and effectiveness of initiating a multidisciplinary sickle cell disease (SCD) obstetrics program for women with SCD in a non-academic hospital. The main question it aims to answer is: In a before-and-after study design, we will test the hypothesis that multidisciplinary care for pregnant women with SCD in a non-academic hospital will result in a 50% relative risk reduction in mortality compared to the mortality rate in pregnant women with SCD in the same hospital before the multidisciplinary care. Participants will be managed using the academic hospital's multidisciplinary sickle cell disease obstetrics protocol adapted for the non-academic hospital

CONDITIONS

Official Title

Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with a confirmed laboratory diagnosis of sickle cell disease
  • Pregnancy confirmed by a pelvic ultrasound scan
  • Pregnancy should be 34 weeks' gestation or less
  • Pregnant women should be aged 18 - 45 years
  • Pregnant women should be attendants at the non-academic hospital
Not Eligible

You will not qualify if you...

  • Pregnant women with sickle cell disease who do not provide informed consent
  • Pregnant women with sickle cell disease referred for management of acute complications and hospital admission
  • Pregnant women with sickle cell disease referred for labor and delivery
  • Pregnant women with SCD who plan to deliver outside the non-academic hospital or cannot adhere to follow-up during the first six weeks after childbirth

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Greater Accra Regional Hospital

Accra, Ghana

Actively Recruiting

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Research Team

D

Dr. Eugenia Vicky N. K. Asare, Senior Specialist Hematologist, MBChB

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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