Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT04807842

Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis

Led by BioClin BV · Updated on 2025-09-29

200

Participants Needed

1

Research Sites

285 weeks

Total Duration

On this page

Sponsors

B

BioClin BV

Lead Sponsor

A

Avania

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a randomized, double-blind, placebo-controlled clinical investigation. The objective of the study is to confirm the efficacy of Multi-Gyn ActiGel Plus to treat BV as compared to a placebo control. Treatment arm 1: Multi-Gyn ActiGel Plus Treatment arm 2: placebo gel Both the Multi-Gyn ActiGel Plus and the placebo will be applied twice a day for 7 consecutive days. Visit 2 will be performed at 3 weeks after start of treatment A phone call will take place, at 5 weeks after start of treatment for subject with clinical cure at Visit 2. The total duration per subject is estimated 5 weeks and the total study duration is 13 months. Sample size is 100 subjects per treatment arm.

CONDITIONS

Official Title

Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women diagnosed with bacterial vaginosis using 3 out of 4 Amsel criteria including at least 20% clue cells
  • Women of childbearing potential
  • Age over 18 years
  • Signed written informed consent
  • Willingness to follow the study schedule
Not Eligible

You will not qualify if you...

  • Having current sexually transmitted or other genital infections such as candidosis or aerobic vaginitis
  • Presence of Trichomonas or Candida Albicans in vaginal smears
  • Current genital cancers
  • Chemotherapy in the last 6 months
  • Radiotherapy to the genitourinary system in the last 12 months
  • Use of antibiotics in the last 14 days
  • Use of intravaginal devices currently or in the last 14 days
  • Pregnancy or trying to conceive
  • Breastfeeding
  • Use of other vaginal treatments during the study
  • Known allergies to study product ingredients
  • Use of medications for vaginal infections or intravaginal medications during the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Praxis Dr. Peters

Hamburg, Germany

Actively Recruiting

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Research Team

D

Diana Zeneli, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis | DecenTrialz