Actively Recruiting
Multi-modal Imaging of Myofascial Pain - Phase 2
Led by Washington University School of Medicine · Updated on 2026-01-07
100
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
N
National Center for Complementary and Integrative Health (NCCIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to evaluate imaging biomarkers for quantitative assessments of myofascial pain and determine their ability to monitor treatment response and predict clinical outcomes.
CONDITIONS
Official Title
Multi-modal Imaging of Myofascial Pain - Phase 2
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults between the ages of 18 and 80 years old
- History of spontaneous (non-provoked) pain in the neck and/or shoulder region lasting at least 3 months
- Presence of a palpable myofascial trigger point in one or both upper trapezius muscles
- Numeric Pain Rating Scale of 4 or more in the last week with pain reproducible by palpation
- Pain localized to the trigger point area that worsens with palpation
- Radiation of pain to head, neck, or face with palpation allowed but not required
You will not qualify if you...
- Younger than 18 or older than 80 years old
- Acute cervical spine problems, trauma, or cervical radiculopathy
- History of surgery involving head, neck, or shoulder girdle
- Neuromuscular or inflammatory muscle diseases such as dermatomyositis
- Systemic diseases causing diffuse body pain such as lupus
- Peripheral neuropathy
- Cancer-related pain
- Pregnancy, bleeding disorders, infection at pain site, substance abuse, or other diseases mimicking myofascial pain
- Contraindications to MRI
- Chronic fatigue syndrome, fibromyalgia, or chronic Lyme disease
- Use of acupuncture or changes in pain medications within 6 weeks prior to enrollment
- Botox injection to neck/shoulder within past 3 months or trigger point injection within past 6 weeks
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
A
Andre Guthrie, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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