Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT07499570

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

Led by Indiana University · Updated on 2026-05-06

60

Participants Needed

1

Research Sites

77 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and Related Dementias (ADRD). SVR is designed to help older adults improve their psychological well-being and cognition. This research supports our long-term goal of designing and implementing intelligent interactive systems to improve the health of individuals with ADRD.

CONDITIONS

Official Title

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged 65 years or older
  • Diagnosed with mild cognitive impairment (MCI) or mild Alzheimer's Disease and Related Dementias (ADRD)
  • Access to a reliable internet connection
  • Living in the community (not in assisted living or nursing home)
  • Elevated behavioral and psychological symptoms of dementia (BPSD) with a Healthy Aging Brain Care monitor score above 14
  • Presence of one or more BPSD behaviors such as agitation, anxiety, depression, apathy, or sleep disturbances
  • Ability to consent for themselves
  • Care partners aged 21 years or older who are knowledgeable about the patient's behaviors and will participate in the study
Not Eligible

You will not qualify if you...

  • Living in an assisted living facility or nursing home
  • Moderate to severe ADRD as measured by the Quick Dementia Rating System
  • Life expectancy less than 6 months
  • Care partner with mild cognitive impairment or dementia
  • Care partner with severe mental illness or substance abuse
  • Care partner with life expectancy less than 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sidney & Lois Eskenazi Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

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Research Team

K

Katrina Coppedge, BA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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