Actively Recruiting

Age: 18Years +
All Genders
NCT05888064

Multi-parametric Imaging in Personalized Radiotherapy

Led by CNAO National Center of Oncological Hadrontherapy · Updated on 2024-08-21

35

Participants Needed

1

Research Sites

173 weeks

Total Duration

On this page

Sponsors

C

CNAO National Center of Oncological Hadrontherapy

Lead Sponsor

D

Dept. of Electronics, Informatics, Bioengineering, Politecnico di Milano, Italy

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study consists in the retrospective and prospective collection of imaging data (along with clinical information related to treatment) of skull-base chordoma patients treated with particle therapy, to derive imaging biomarkers which, integrated with advanced mathematical models, will allow predicting treatment outcome on a multi-scale basis.

CONDITIONS

Official Title

Multi-parametric Imaging in Personalized Radiotherapy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with histologically confirmed diagnosis of chordoma of the skull base
  • Particle therapy with curative intent
  • Karnofsky Performance status greater than or equal to 60
  • Patients with macroscopic disease detectable at pre-radiotherapy imaging
  • Patients undergoing PT with standardized treatment procedures
  • Patients who have signed the written informed consent for research
Not Eligible

You will not qualify if you...

  • Metastatic disease
  • Palliative treatment
  • Other malignancies with disease-free interval < 5 years (excepting pre-cancerous lesions)
  • Pregnancy
  • Simultaneous CHT or Immunotherapy
  • Extensive metal instrumentation/implants
  • Patients with autoimmune diseases (ADs) -including collagen-vascular (CVD) and inflammatory bowel (IBD)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CNAO

Pavia, Pv, Italy, 27100

Actively Recruiting

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Research Team

A

Alberto Iannalfi, MD

CONTACT

C

Cristina Bono, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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