Actively Recruiting
Multi-parametric Magnetic Resonance Imaging for the Precise Diagnosis and Quantitative Study of Liver Steatosis, Inflammation, and Fibrosis in Chronic Liver Disease.
Led by Shengjing Hospital · Updated on 2025-02-28
100
Participants Needed
1
Research Sites
167 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To construct a novel, non-invasive, accurate, and convenient method to achieve the degree of liver damage is an important general problem in the management of patients with chronic liver disease. The investigators would like to develop non invasive advanced Magnetic Resonance Imaging (MRI) techniques (MR elastography, MRI-PDFF) to assess the degree of liver damage in patients with chronic liver disease. These techniques could reach high diagnostic performance for detection of liver fibrosis, inflammation and liver fat content; and could decrease the number of liver biopsies, which have risks and sample only a small portion of the liver.
CONDITIONS
Official Title
Multi-parametric Magnetic Resonance Imaging for the Precise Diagnosis and Quantitative Study of Liver Steatosis, Inflammation, and Fibrosis in Chronic Liver Disease.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Have chronic liver disease, including viral hepatitis, alcoholic hepatitis, nonalcoholic steatohepatitis, primary biliary cirrhosis, or primary sclerosing cholangitis
- Are between 18 and 75 years old
- Are willing to accept systematic antiviral therapy, hormone therapy, ursodesoxycholic acid, or supportive liver protection therapy
You will not qualify if you...
- Are younger than 18 years old
- Are unable or unwilling to give informed consent
- Have contraindications to MRI
- Have electrical implants such as cardiac pacemakers or perfusion pumps
- Have ferromagnetic implants like aneurysm clips, surgical clips, prostheses, artificial hearts, metal fragments, or tattoos near the eye
- Have ferromagnetic objects such as jewelry or metal clips in clothing
- Are pregnant
- Have medical conditions that increase the risk of seizures or claustrophobia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shengjing Hospital of China Medical University
Shenyang, Liaoning, China, 110004
Actively Recruiting
Research Team
Y
Yu Shi
CONTACT
R
Ruobing Bai
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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