Pilot Study of a Multi-Strain Liquid Probiotic for Adults With Self-Reported Constipation

What this Trial Is About

Constipation is a common digestive problem that many people face. While lifestyle changes like increasing fiber, hydration, and exercise are often suggested, some individuals are not satisfied with usual drug treatments. Researchers are studying a multi-strain live bacterial probiotic supplement to see if it can help improve symptoms and quality of life in people who report having constipation. This pilot study aims to include 20 participants to better understand how this probiotic may work for those with mild constipation. Participants will take 70 ml of the multi-strain liquid probiotic once daily on an empty stomach for 28 to 35 days. They are asked to wait 10 minutes after taking the supplement before eating or drinking. This study focuses on assessing changes in constipation symptoms and gut function during this treatment period. During the study, participants will be evaluated using the Patient Assessment of Constipation-Symptoms PAC-SYM before and after 28 days of probiotic use. Other assessments include quality of life measures, gut transit times, stool frequency and form, gastrointestinal symptoms, and gas production. Participants will also keep a daily bowel diary and follow pre-test preparations for gut transit studies. The study is designed to monitor symptom improvements and treatment adherence over about one month.

Multi-strain Probiotic Effects on Self-Reported Constipation