Actively Recruiting
Multicenter, Interdisciplinary National VEXAS Registry With Accompanying Biomaterial Collection
Led by Technische Universität Dresden · Updated on 2026-05-15
500
Participants Needed
17
Research Sites
52 weeks
Total Duration
On this page
Sponsors
T
Technische Universität Dresden
Lead Sponsor
B
Bristol-Myers Squibb
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to rapidly gather real-world information about VEXAS syndrome, focusing on its epidemiology, treatments, and disease progression during standard medical care. It also collects biomaterials to study links between genetic makeup and symptoms, to find the best treatment plans, and to identify key diagnostic features and biomarkers. The study is observational, involving patients with confirmed or suspected VEXAS syndrome aged 18 or older who provide consent. There are no assigned treatments or interventions as it records information during routine clinical practice. The registry collects data and biospecimens over a period of up to five years to support detailed analysis. Participants will provide clinical data, treatment histories, and quality of life information through questionnaires and laboratory tests. Researchers will monitor disease manifestations, treatments, and clinical outcomes, as well as collect biosamples for translational research. The study follows participants for up to five years to better understand VEXAS syndrome and its management.
CONDITIONS
Brief Title
Multicenter, Interdisciplinary National VEXAS Registry With Accompanying Biomaterial Collection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with established or suspected (clinical and hematological criteria) VEXAS Syndrome
- Age 65 18 years
- Signed informed consent form
You will not qualify if you...
- Patients who are not in a position to understand the nature and scope of participation in this register
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 5 years
Participants are observed over time to collect epidemiological data, monitor disease manifestations, document treatments, and analyze clinical outcomes.
Periodic visits over 5 years
Trial Site Locations
Total: 17 locations
1
Universitätsklinikum Aachen
Aachen, Germany
Actively Recruiting
2
Klinikum Chemnitz gGmbH
Chemnitz, Germany
Actively Recruiting
3
Universitätsklinikum Carl Gustav Carus
Dresden, Germany, 01307
Actively Recruiting
4
Universitätsklinikum Düsseldorf
Düsseldorf, Germany
Actively Recruiting
5
Evang. Kliniken Essen-Mitte
Essen, Germany
Actively Recruiting
6
Universitätsmedizin Göttingen
Göttingen, Germany
Actively Recruiting
7
Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany
Actively Recruiting
8
Universitätsklinikum Jena
Jena, Germany
Actively Recruiting
9
Universitätsklinikum Leipzig AöR
Leipzig, Germany
Actively Recruiting
10
Universitätsmedizin Mannheim
Mannheim, Germany
Actively Recruiting
11
Klinikum rechts der Isar TUM
München, Germany
Actively Recruiting
12
Klinikum Nürnberg, Campus Nord
Nuremberg, Germany
Actively Recruiting
13
Klinikum Osnabrück GmbH
Osnabrück, Germany
Actively Recruiting
14
Helios Kliniken Schwerin GmbH
Schwerin, Germany
Actively Recruiting
15
Robert Bosch Gesellschaft für Medizinische Forschung mb
Stuttgart, Germany
Actively Recruiting
16
Krankenhaus der Barmherzigen Brüder
Trier, Germany
Actively Recruiting
17
Universitätsklinikum Tübingen
Tübingen, Germany
Actively Recruiting
Research Team
K
Katja Sockel, Dr. med.
K
Katharina Goetze, Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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