Actively Recruiting

Age: 18Years +
All Genders
NCT06779435

A Multicenter, Prospective, Real-world Study of a Regimen Containing Tucidinostat for Primary Treatment of DLBCL

Led by Ruijin Hospital · Updated on 2025-02-19

400

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, observational, multicenter, cohort study with 400 newly treated DLBCL patients. To evaluate the clinical efficacy and safety of tucidinostat in the real-world treatment of primary diffuse large B-cell lymphoma

CONDITIONS

Official Title

A Multicenter, Prospective, Real-world Study of a Regimen Containing Tucidinostat for Primary Treatment of DLBCL

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older, male or female
  • No prior treatment for DLBCL, including chemotherapy, targeted therapy, or immunotherapy
  • Confirmed diffuse large B-cell lymphoma with double expression of MYC and BCL2 by pathology, or presence of TP53 or other epigenetic gene mutations, or MYC and BCL2 double hit
  • Plan to receive or currently receiving a treatment regimen containing tucidinostat
  • Voluntarily sign informed consent
Not Eligible

You will not qualify if you...

  • Currently enrolled or planning to participate in any interventional clinical trial
  • Expected survival time less than 6 months
  • Any other reason deemed unsuitable by the investigators for participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

No. 197 Ruijin 2nd Road, Huangpu District, Shanghai

Shanghai, Shanghai Municipality, China

Actively Recruiting

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Research Team

P

Pengpeng Xu, professor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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A Multicenter, Prospective, Real-world Study of a Regimen Containing Tucidinostat for Primary Treatment of DLBCL | DecenTrialz