Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT07351669

A Multicenter Prospective Study on the Performance of Spectral CT for Evaluating Treatment Response After TACE in Hepatocellular Carcinoma

Led by Zhongda Hospital · Updated on 2026-03-19

250

Participants Needed

1

Research Sites

127 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

By comparing the diagnostic accuracy of spectral CT and conventional CT in evaluating treatment response efficacy after TACE, this study aims to investigate the diagnostic performance of spectral CT in assessing treatment response following TACE for hepatocellular carcinoma.

CONDITIONS

Official Title

A Multicenter Prospective Study on the Performance of Spectral CT for Evaluating Treatment Response After TACE in Hepatocellular Carcinoma

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Voluntary participation and ability to sign informed consent after TACE
  • Age between 18 and 75 years
  • Diagnosed with hepatocellular carcinoma (HCC) based on pathology or clinical criteria, with BCLC stage A or B
  • Underwent contrast-enhanced spectral CT 4-8 weeks after treatment and assessed as complete response on conventional CT images
  • Scheduled for surgical resection within one month, or DSA hepatic arteriography or contrast-enhanced MRI within one week, or planned imaging follow-up every 3 months for at least one year
  • Patients planning liver tumor resection following TACE downstaging therapy
  • Performed contrast-enhanced spectral CT within 7 days before liver resection after completion of TACE down-staging treatment
Not Eligible

You will not qualify if you...

  • Contraindications to contrast-enhanced CT or contrast-enhanced MRI
  • Presence of extrahepatic malignancies
  • History of radiotherapy
  • Poor image quality or incomplete clinical or imaging data
  • Withdrawal from the study midway

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhongda Hospital Southeast University

Nanjing, China

Actively Recruiting

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Research Team

S

Shuhang Zhang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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A Multicenter Prospective Study on the Performance of Spectral CT for Evaluating Treatment Response After TACE in Hepatocellular Carcinoma | DecenTrialz