Actively Recruiting

Age: 1Year +
All Genders
ID07343089

A Multicenter Real-life Study of Disseminated Borreliosis Cases Occurring in Patients Receiving Anti-CD20 Treatment in France

Led by University Hospital, Strasbourg, France · Updated on 2026-01-15

100

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research investigates cases of disseminated borreliosis, an infection caused by Borrelia burgdorferi sl. and Borrelia miyamotoi, in patients who have received treatment with anti-CD20 monoclonal antibodies. The study aims to clinically, biologically, radiologically, and pharmacologically describe these cases to better understand the infection among this specific patient group in France. The study is observational and collects data from patients who developed disseminated borreliosis within 24 months after receiving anti-CD20 therapy between January 2010 and July 2025. It does not involve administering treatments but focuses on monitoring and describing the disease's presentation and course. Participants will be evaluated for up to 12 months, during which researchers will document the clinical presentation of borreliosis cases. The study involves collecting medical information and biological data to characterize the infection. There is no intervention, and participants' usual medical care continues throughout the observation period.

CONDITIONS

Brief Title

A Multicenter Real-life Study of Disseminated Borreliosis Cases Occurring in Patients Receiving Anti-CD20 Treatment in France

Who Can Participate

Age: 1Year +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Minor or adult subject
  • Confirmed disseminated borreliosis by molecular biology (Borrelia burgdorferi sl. or Borrelia miyamotoi)
  • Diagnosis within 24 months of receiving anti-CD20 monoclonal antibody treatment between January 1, 2010, and July 30, 2025
Not Eligible

You will not qualify if you...

  • Refusal to participate in the study

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Long-term Monitoring

Duration - Up to 12 months

Participants are observed to describe the clinical presentation of disseminated borreliosis occurring in patients receiving anti-CD20 therapy.

Trial Site Locations

Total: 1 location

1

Laboratoire de Bactériologie - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

P

Pierre BOYER, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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