Actively Recruiting

Age: 1Year - 18Years
All Genders
ID07305168

A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea

Led by University Hospital, Antwerp · Updated on 2025-12-26

200

Participants Needed

2

Research Sites

60 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate postoperative respiratory complications (PORC) in children with obstructive sleep apnea (OSA) who undergo (adeno)tonsillectomy. It combines data from two centers: University Hospital Antwerp and Heim Pal National Pediatric Institute in Hungary. The study examines how common these complications are and whether they vary according to different health conditions such as obesity, craniofacial malformations, Down syndrome, or neurological disorders that affect airway muscle tone. Data come from a retrospective analysis of electronic health records originally collected in two prospective studies. These records include children who had (adeno)tonsillectomy for OSA, with postoperative care following a set protocol. The study looks at factors like the obstructive apnea-hypopnea index, oxygen levels during sleep studies, age at surgery, and presence of other health conditions to understand their relationship with PORC and to help develop a management plan. Participants' information was collected without needing additional consent because it uses existing anonymized data. Researchers assess the prevalence of PORC within 24 hours after surgery and analyze how different factors affect this risk. This study does not involve new treatments but reviews existing data to improve postoperative care. The study includes children aged 1 to 18 years who had (adeno)tonsillectomy for OSA, with follow-up limited to the immediate postoperative period.

CONDITIONS

Brief Title

A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea

Who Can Participate

Age: 1Year - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for (adeno)tonsillectomy as treatment for obstructive sleep apnea
Not Eligible

You will not qualify if you...

  • Undergoing surgery other than (adeno)tonsillectomy for obstructive sleep apnea
  • No polysomnography available within 1 year before surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Up to 1 year before surgery

Participants undergo polysomnography to assess obstructive sleep apnea severity before surgery.

1 diagnostic visit (in-person)

Surgery and Immediate Post-operative Care

Duration - 24 hours post-operative

Participants undergo (adeno)tonsillectomy and receive post-operative management according to a predefined treatment protocol.

Approximately 1 post-operative period

Post-operative Follow-up

Duration - Retrospective observation period

Participants are observed for postoperative respiratory complications using existing electronic health record data.

Trial Site Locations

Total: 2 locations

1

Antwerp University Hospital

Edegem, Antwerp, Belgium, 2650

Actively Recruiting

2

Heim Pal Children's Hospital

Budapest, Hungary, 1089

Completed

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Research Team

V

Vera Saldien, MD

J

Joke De Wachter

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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