Actively Recruiting

Age: 18Years +
All Genders
NCT07056023

Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors

Led by University Hospital Muenster · Updated on 2025-07-09

100

Participants Needed

1

Research Sites

134 weeks

Total Duration

On this page

Sponsors

U

University Hospital Muenster

Lead Sponsor

T

Technical University of Munich

Collaborating Sponsor

AI-Summary

What this Trial Is About

Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary objectives: Assessment of variables leading to better outcome through regression analysis: 1. Influence of surgical approach on functionality, pain, and quality of life 2. Comparison between patient with severe neurological (McCormick scale 3-5) to patients with mild deficits (McCormick scale 1-2) 3. Role of intraoperative monitoring (IOM) in extent of resection and neurological deficits Assessment of treatment variations: 1. Assessment of risk factors for incomplete resection 2. Non inferiority of unilateral approach to achieve gross total resection of spinal meningioma, schwannoma and cauda ependymoma 3. Role of bed rest after surgery to prevent cerebro-spinal fluid leakage 4. Influence of laminectomy on cerebro-spinal fluid leakage Quality indicators: assessments of length of hospital stay, 30- and 90-days re-admissions, 30- and 90-days re-surgery, nosocomial infections

CONDITIONS

Official Title

Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult, age 618 years, patients treated on intraspinal, extra medullary tumor
  • Patients must have sufficient cognitive and language skills to give informed consent
Not Eligible

You will not qualify if you...

  • Absence of informed consent
  • Lack of ability to consent
  • Primary bone tumors invading the intra-spinal space
  • Vertebral metastasis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Muenster

Münster, Nordrhien Westfalen, Germany, 48167

Actively Recruiting

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Research Team

M

Michael Schwake, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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