Actively Recruiting
Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
Led by University Hospital Muenster · Updated on 2025-07-09
100
Participants Needed
1
Research Sites
134 weeks
Total Duration
On this page
Sponsors
U
University Hospital Muenster
Lead Sponsor
T
Technical University of Munich
Collaborating Sponsor
AI-Summary
What this Trial Is About
Primary objectives: Primary objectives are to assess and define benchmarks of the surgical outcome in the form of extent of resection, functionality, and quality of life after resection of juxta medullary tumors Secondary objectives: Assessment of variables leading to better outcome through regression analysis: 1. Influence of surgical approach on functionality, pain, and quality of life 2. Comparison between patient with severe neurological (McCormick scale 3-5) to patients with mild deficits (McCormick scale 1-2) 3. Role of intraoperative monitoring (IOM) in extent of resection and neurological deficits Assessment of treatment variations: 1. Assessment of risk factors for incomplete resection 2. Non inferiority of unilateral approach to achieve gross total resection of spinal meningioma, schwannoma and cauda ependymoma 3. Role of bed rest after surgery to prevent cerebro-spinal fluid leakage 4. Influence of laminectomy on cerebro-spinal fluid leakage Quality indicators: assessments of length of hospital stay, 30- and 90-days re-admissions, 30- and 90-days re-surgery, nosocomial infections
CONDITIONS
Official Title
Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult, age 618 years, patients treated on intraspinal, extra medullary tumor
- Patients must have sufficient cognitive and language skills to give informed consent
You will not qualify if you...
- Absence of informed consent
- Lack of ability to consent
- Primary bone tumors invading the intra-spinal space
- Vertebral metastasis
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospital Muenster
Münster, Nordrhien Westfalen, Germany, 48167
Actively Recruiting
Research Team
M
Michael Schwake, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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