Actively Recruiting
Multicentric Study on Urinary Tract Infections After Ureteral Stent Removal Observational Study Evaluating Infection Rates With or Without Antibiotic Use
Led by University Hospital, Ghent · Updated on 2025-01-15
1000
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Ghent
Lead Sponsor
A
AZ Sint-Lucas Gent
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying urinary tract infections (UTIs) that may occur after removal of ureteral stents in adults aged 18 and older. This multicenter, multinational observational study aims to understand the incidence of UTIs after stent removal with or without antibiotic use in patients who had a sterile urine culture before stent placement and no infection during the time the stent was in place. The study also seeks to identify risk factors for UTIs following stent removal and compare infection rates between stents removed in an outpatient clinic versus those removed by patients at home using a string. Patients receiving ureteral stents during endoscopic procedures will have their stents removed either in an outpatient office or at home by string extraction. Antibiotic use during stent removal will vary according to standard care at each participating center. Before stent removal, a urine sample will be collected. Following removal, patients will complete a questionnaire about symptoms of urinary tract infection. If symptoms such as urgency, frequency, pain during urination, or blood in urine exceed usual post-procedure discomfort, patients will provide an additional urine sample for testing. Throughout the study, researchers will monitor participants for signs of febrile and non-febrile UTIs within 30 days after stent removal. The main measure is the number of participants who develop UTIs following stent removal. This includes evaluations through symptom questionnaires and urine tests. The study will also track safety and infection rates over time, helping to guide future recommendations on antibiotic use and stent removal practices. Participation involves urine testing, symptom reporting, and follow-up within a month after the stent is taken out.
CONDITIONS
Official Title
Multicentric Study on Infections of the Urinary Tract After Stent Removal (MINUS-trial).
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 years or above
- Stent placed during endoscopic procedure
- Negative urine culture before procedure with single dose antibiotic given around procedure time
- Stent removal planned in outpatient setting or by patient using a string
- Able and willing to provide consent
You will not qualify if you...
- Permanent indwelling urinary catheter or nephrostomy tubes
- Pregnant patients
- Patients performing clean intermittent self-catheterization
- Recent urinary tract infection within the past 3 months
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University Hospital Ghent
Ghent, Eastern-Flanders, Belgium, 9000
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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