Actively Recruiting

Phase Not Applicable
Age: 65Years - 89Years
All Genders
NCT04715581

Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty

Led by Peking University First Hospital · Updated on 2025-07-31

540

Participants Needed

1

Research Sites

366 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study is designed to investigate the effect of a multicomponent prehabilitation pathway on early and long-term outcomes in elderly patients with frailty recovering from surgery for digestive cancer.

CONDITIONS

Official Title

Multicomponent Prehabilitation and Outcomes in Elderly Patients With Frailty

Who Can Participate

Age: 65Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 years or older but younger than 90 years
  • Scheduled for major surgery lasting 2 hours or longer for digestive cancers including esophagus, stomach, small intestine, colon, rectum, pancreas, liver, or biliary tract
  • Clinical Frailty Scale score of 5 or greater
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • History of schizophrenia, epilepsy, Parkinsonism, or myasthenia gravis before surgery
  • Unable to communicate due to coma, severe dementia, or language barriers
  • Unable to participate in preoperative rehabilitation because of paralysis, fracture, or other movement disorders
  • Unable to eat oral diet due to gastrointestinal or other diseases
  • Severe heart dysfunction (left ventricular ejection fraction less than 30% or NYHA class IV), severe liver dysfunction (Child-Pugh class C), severe kidney dysfunction requiring dialysis before surgery, or ASA classification grade 4 or higher
  • Other conditions making study participation unsuitable

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University First Hospital

Beijing, Beijing Municipality, China, 100034

Actively Recruiting

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Research Team

D

Dong-Xin Wang, MD

CONTACT

H

Huai-Jin Li, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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