Actively Recruiting

Age: 18Years - 45Years
FEMALE
NCT06047574

Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome

Led by Shanghai 10th People's Hospital · Updated on 2026-03-09

3000

Participants Needed

1

Research Sites

149 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators collected clinical data and serum samples of patients with polycystic ovary syndrome (PCOS) in this study, used statistical software such as SPSS for date analysis, and used experimental techniques such as ELISA and flow cytometry to detect serum samples, aiming to explore the relationship between the body anthropometry, skin conditions, psychosomatic status, diet, sleep, exercise, glucose and lipid metabolism, gonadal hormones, and body fat distribution in patients with polycystic ovary syndrome, and to discovery new biomarkers. Multidisciplinary exploration of the mechanisms of disease occurrence and development, the establishment of a PCOS multicenter, multidisciplinary and multidimensional clinical research database, combined with the established statistical analysis strategy for big data and analysis, to promote the realization of more accurate personalized medicine.

CONDITIONS

Official Title

Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female aged 18- 45
Not Eligible

You will not qualify if you...

  • Female patients younger than 18 years old or older than 45 years old
  • Ovulatory disorders caused by premature ovarian failure, pituitary amenorrhea, hypothalamic amenorrhea, and thyroid dysfunction
  • Congenital adrenal hyperplasia, reservoir Hin syndrome, hyperprolactinemia, adrenal tumors and other diseases that cause hyperandrogenism
  • Abnormal liver or renal function (≥ 3 times of the upper limit of normal range)
  • Type 1 diabetes, single gene mutation diabetes, pancreatic damage diabetes or other secondary diabetes caused by diabetes
  • History of malignant tumors
  • Severe infection, severe anemia, neutropenia and other systemic chronic diseases
  • Undergo total hysterectomy or ovarian adnexectomy
  • Mental illness, dementia or other cognitive behavioral problems
  • Use hypoglycemic drugs affecting insulin resistance and androgen levels in the last 3 months, including thiazolidinediones, metformin, SGLT-2, acarbose, GLP-1RA and others
  • Use letrozole, clomiphene, oral contraceptives, glucocorticoids, gonadotropins, gonadotropin-releasing hormone agonists, anti-androgens (spironolactone, Cyproterone acetate, flutamide, etc.) and other drugs for PCOS treatment

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Endocrinology, Shanghai Tenth People's Hospital

Shanghai, Shanghai Municipality, China, 200070

Actively Recruiting

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Research Team

M

Manna Zhang, Dr

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Multidisciplinary Diagnosis and Treatment of Polycystic Ovary Syndrome | DecenTrialz