Actively Recruiting
Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma
Led by Third Affiliated Hospital, Sun Yat-Sen University · Updated on 2023-08-15
45
Participants Needed
1
Research Sites
569 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to retrospectively and prospectively analyze the efficacy and safety of ultrasound-guided radiofrequency ablation and laparoscopic adrenalectomy in the treatment of aldosterone-producing adenoma (APA). It is planned to retrospectively collect 30 patients with adrenal radiofrequency ablation for APA and 15 patients with age - and sex-matched laparoscopic adrenalectomy for APA in our hospital from January 2020 to June 2024, and continue to follow up for 3 years.
CONDITIONS
Official Title
Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed unilateral aldosterone-producing adenoma (APA)
- Benign tumor without adrenal metastasis or tumor embolus
- Undergoing ultrasound-guided adrenal radiofrequency ablation or laparoscopic adrenalectomy with informed consent
- Age 18 years or older
- For participants 40 years or older: blood potassium level ≤ 3.5 mmol/L, plasma aldosterone concentration ≥ 20 ng/dL, plasma renin concentration ≤ 5 μIU/mL, and a unilateral adrenal nodule of 10 mm or more with the opposite side normal
You will not qualify if you...
- Bilateral adrenal diseases
- Multiple adrenal tumors
- Other adrenal diseases such as adrenal hyperplasia, Cushing's syndrome, or pheochromocytoma
- Tumor location difficult to reach based on imaging
- Imaging suggests potentially malignant adrenal tumor
- Pregnant or planning pregnancy
- Refusal to participate in follow-up visits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Third Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China, 510000
Actively Recruiting
Research Team
X
Xubin Yang, Dr
CONTACT
H
Huan Xu, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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