Actively Recruiting
Multifaceted Intervention to Restore Resilience and Overcome Risk in Female Veterans with Military Sexual Trauma, Intimate Partner Violence, Brain Injury, and PTSD
Led by Icahn School of Medicine at Mount Sinai · Updated on 2025-12-10
136
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
I
Icahn School of Medicine at Mount Sinai
Lead Sponsor
B
Baylor College of Medicine
Collaborating Sponsor
AI-Summary
What this Trial Is About
Female Veterans who have experienced military sexual trauma (MST) and/or intimate partner violence (IPV) often face a higher risk of brain injury (BI) and psychological challenges, including post-traumatic stress disorder (PTSD). This research aims to evaluate the effectiveness of two combined interventions in improving emotion regulation and reducing PTSD symptoms in this group. The study focuses on those with sub-threshold PTSD and documented emotional regulation difficulties, seeking to address the combined effects of MST, IPV, and BI. Participants will be randomly assigned to one of two treatment groups: one will receive a web-based emotion regulation program called webSTAIR followed by exposure therapy (ExpoTx), while the other will receive psychoeducation (PsychEd) followed by the same exposure therapy. The webSTAIR program involves completing 10 online skill modules over five weeks with therapist support via video-telehealth, followed by five weekly one-hour virtual exposure therapy sessions. The psychoeducation group will have five online sessions covering mental health topics related to trauma before starting the exposure therapy. During the study, participants will undergo assessments measuring difficulties in emotion regulation, PTSD symptoms, depression, anxiety, interpersonal problems, brain injury effects, and quality of life at multiple time points up to three months after treatment. These evaluations include questionnaires and scales like the Difficulties in Emotion Regulation Scale and the PTSD Checklist for DSM-5. The study also involves ongoing monitoring and aims to understand how improvements in emotion regulation affect treatment outcomes and lasting benefits.
CONDITIONS
Brief Title
Multifaceted Intervention to Restore Resilience and Overcome Risk
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to consent and are English-speaking female Veterans 18 years or older
- Screen positive for exposure to intimate partner violence and/or military sexual trauma
- Have a history of at least one brain injury
- Have sub-threshold PTSD with a total score greater than 33 on the PTSD Checklist for DSM-5
- Report difficulties in emotion regulation with scores above average on the Difficulties in Emotion Regulation Scale
You will not qualify if you...
- Female Veterans at high risk for suicide based on specific items on the Columbia Suicide Severity Rating Scale
- Observable active psychosis, such as auditory hallucinations or grandiose delusions
- Problematic substance use with a high score on the Alcohol, Smoking and Substance Involvement Screening Test leading to referral for treatment and possible exclusion from the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
screening and enrollment visit
Duration - 10 weeks
Participants complete either a web-based emotion regulation program or psycho-education sessions, each followed by exposure therapy sessions conducted virtually with a therapist.
Weekly visits for up to 10 weeks, including therapist support and exposure therapy sessions
Duration - 3 months
Participants are monitored to assess maintenance of treatment gains after completing the intervention.
1 follow-up visit at 3 months post-treatment
Trial Site Locations
Total: 1 location
1
Baylor College of Medicine
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
M
Maria Kajankova, PhD
M
Madelyn Olis, BA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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