Actively Recruiting
A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in Children
Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2026-04-09
5249
Participants Needed
1
Research Sites
19 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to develop and validate a multimodal artificial intelligence prediction model for treatment-related complications in children with perimembranous ventricular septal defect (pmVSD) undergoing transcatheter device closure. The main question it aims to answer is: Can an AI model that integrates demographics, laboratory results, electronic health record text, echocardiography reports, chest radiographs, and electrocardiogram accurately predict the risk of complications at the individual patient level? Data will be retrospectively collected from routine clinical care records of pediatric patients who underwent transcatheter closure for pmVSD. Deep learning methods will be used to extract features from text and images to train and validate the prediction model.
CONDITIONS
Official Title
A Multimodal AI Prediction Model for Complications After Transcatheter Closure of Perimembranous VSD in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or younger at the time of transcatheter procedure
- Diagnosis of perimembranous ventricular septal defect confirmed by echocardiography
- Underwent transcatheter device closure at the study center
- Medical records sufficient to determine primary outcome within follow-up period
- Availability of minimum baseline clinical information for model development and validation
You will not qualify if you...
- Ventricular septal defects not classified as perimembranous (including muscular, outlet, inlet VSDs, or multiple/complex VSDs involving more than one septal region)
- Presence of complex congenital heart disease or structural abnormalities requiring surgical repair (e.g., tetralogy of Fallot)
- Prior surgical repair or prior transcatheter closure of ventricular septal defect
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200092
Actively Recruiting
Research Team
K
Kun Sun
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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