Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT07587320

Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Led by Saglik Bilimleri Universitesi · Updated on 2026-05-14

56

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery. This prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting. Patients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.

CONDITIONS

Official Title

Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years
  • Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting
  • ASA physical status II-IV
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Known coagulopathy or contraindication to regional anesthesia
  • Use of anticoagulant therapy precluding regional block
  • Known allergy to local anesthetics
  • Local infection at planned block sites
  • Chronic opioid use or chronic pain syndrome
  • Emergency surgery
  • Redo sternotomy
  • Severe neurological disorder affecting pain assessment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Health Sciences, Diyarbakir Gazi Yasargil Training and Research Hospital

Diyarbakır, Diyarbakır, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Selen Topalel, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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