Actively Recruiting
Multimodal Imaging Assessment of Chronic Kidney Disease Patients at Different Stages From a Cardio-Renal Interaction Perspective
Led by The Affiliated Hospital of Qingdao University · Updated on 2025-08-06
60
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective cohort investigation in which consecutive eligible patients undergo 18F-FAPI PET/MR imaging. Chronic kidney disease (CKD) participants are stratified into two groups:Group I ：CKD stages 1-3（eGFR ≥ 30 mL/min/1.73 m²）,Group II :CKD stages 4-5(eGFR \< 30 mL/min/1.73 m²). Using 18F-FAPI PET/MR, we will evaluate global cardiac functional impairment and myocardial fibrosis characteristics, and analyze their associations with the degree of renal dysfunction.
CONDITIONS
Official Title
Multimodal Imaging Assessment of Chronic Kidney Disease Patients at Different Stages From a Cardio-Renal Interaction Perspective
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years, regardless of sex
- Diagnosed with chronic kidney disease based on KDIGO guidelines
- Complete clinical data available
- Provided written informed consent for participation and 18F-FAPI PET/MR imaging
- Female participants agree to use effective contraception during the study and for 6 months after
- Male participants agree to use contraception during the study and for 6 months after
You will not qualify if you...
- Women planning to conceive, currently pregnant, or breastfeeding
- Contraindications to PET/MR imaging such as metal implants, claustrophobia, or inability to tolerate cardiac MRI
- History of allergy or hypersensitivity to gadolinium-based contrast agents
- Presence of malignant tumors or other serious progressive diseases
- Severe cardiac conditions including advanced heart failure, severe valvular disease, or cardiomyopathies
- Hemodynamic instability
- Severe systemic or localized infections or other serious comorbid conditions
- Incomplete clinical data
- Any other reason deemed unsuitable by investigators including inability or unwillingness to comply with study procedures
- Investigator-determined inappropriate candidates for inclusion
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China, 266003
Actively Recruiting
Research Team
P
Pei Nie, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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